Table 3.
Results of logistic regressions showing association of outcome (death, recovery, chronicity/recurrence) with variables of interest.
| Outcome: Death (n = 53) | |||
|---|---|---|---|
| Variable | OR | 95%CI | p Value |
| Surgical treatment | 0.687 | [0.376–1.290] | 0.23 |
| Treatment duration, months | 0.54 | [0.411–0.675] | <0.001 |
| Time to diagnosis 0–1 month 1–6 months >6 months |
0.712 1.541 0.930 |
[0.382–1.287] [0.863 2.759] [0.391 1.966] |
0.27 0.143 0.859 |
| Immunocompromised | 1.507 | [0.837–2.798] | 0.18 |
| Site of infection Basicranium Extremities (except foot) Foot Other cranium bones Pelvis and hip Ribs and sternum Shoulder Splanchnocranium Vertebrae |
1.282 0.598 - 1.968 0.412 1.127 0.493 0.794 1.762 |
[0.423–3.185] [0.293–1.140] - [0.884–4.054] [0.066–1.405] [0.472–2.396] [0.027–2.492] [0.294–1.808] [0.957–3.176] |
0.622 0.135 - 0.078 0.232 0.768 0.497 0.613 0.063 |
| Aetiological agents Aspergillus Blastomyces Candida Coccidioides Cryptococcus Fusarium Histoplasma Mucormycosis Paracoccidioides Phaeohyphomycosis Scedosporium Other |
2.69 - 0.682 0.390 0.597 3.135 0.611 1.231 - - 0.792 1.269 |
[1.498–4.829] - [0.289–1.427] [0.021–1.934] [0.222–1.348] [0.670–11.236] [0.033–3.163] [0.450–2.865] - - [0.185–2.329] [0.291–3.893] |
<0.001 - 0.343 0.364 0.254 0.099 0.638 0.653 - - 0.709 0.709 |
| Outcome: Recovery (n = 399) | |||
| Variable | OR | 95%CI | p Value |
| Surgical treatment | 1.541 | [0.913–2.561] | 0.98 |
| Treatment duration, months | 1.144 | [1.060–1.252] | 0.001 |
| Time to diagnosis 0–1 month 1–6 months >6 months |
1.075 1.098 0.704 |
[0.659–1.771] [0.673–1.808] [0.387–1.335] |
0.772 0.619 0.693 |
| Immunocompromised | 0.835 | [0.507–1.358] | 0.472 |
| Site of infection Basicranium Extremities (except foot) Foot Other cranium bones Pelvis and hip Ribs and sternum Shoulder Splanchnocranium Vertebrae |
0.847 1.373 7.358 0.684 1.112 0.706 0.933 1.143 0.514 |
[0.377–2.165] [0.811–2.402] [1.551–131.77] [0.352–1.418] [0.481–3.031] [0.378–1.391] [0.296–4.118] [0.578–2.476] [0.312–0.857] |
0.707 0.25 0.051 0.282 0.818 0.292 0.915 0.716 0.009 |
| Aetiological agents Aspergillus Blastomyces Candida Coccidioides Cryptococcus Fusarium Histoplasma Mucormycosis Paracoccidioides Phaeohyphomycosis Scedosporium Other |
0.646 3.732 1.003 0.845 1.737 0.458 2.66 0.975 - - 0.895 0.513 |
[0.389–1.087] [0.754–67.632] [0.561–1.879] [0.303–3] [0.869–3.873] [0.124–2.162] [0.518–48.68] [0.458–2.326] - - [0.379–2.465] [0.203–1.471] |
0.094 0.203 0.992 0.768 0.143 0.266 0.349 0.951 - - 0.813 0.179 |
| Outcome: Recurrence/Chronicity (n = 62) | |||
| Variable | OR | 95%CI | p Value |
| Surgical treatment | 1.266 | [0.696–2.422] | 0.455 |
| Treatment duration, months | 1.088 | [1.039–1.142] | <0.001 |
| Time to diagnosis 0–1 month 1–6 months >6 months |
0.896 0.478 3.048 |
[0.512–1.545] [0.257–0.850] [1.643–5.534] |
0.698 0.014 <0.001 |
| Immunocompromised | 0.661 | [0.385–1.129] | 0.129 |
| Site of infection Basicranium Extremities (except foot) Foot Other cranium bones Pelvis and hip Ribs and sternum Shoulder Splanchnocranium Vertebrae |
0.363 1.024 0.827 0.975 2.184 1.643 2.953 1.091 1.461 |
[0.057–1.233] [0.568–1.793] [0.240–2.182] [0.387–2.138] [0.933–4.692] [0.791–3.199] [0.912–8.286] [0.481–2.239] [0.814–2.557] |
0.171 0.934 0.73 0.954 0.055 0.16 0.049 0.821 0.192 |
| Aetiological agents Aspergillus Blastomyces Candida Coccidioides Cryptococcus Fusarium Histoplasma Mucormycosis Paracoccidioides Phaeohyphomycosis Scedosporium Other |
1.001 0.782 1.206 1.618 0.487 0.665 3.966 0.802 - 1.688 1.215 1.069 |
[0.537–1.789] [0.122–2.821] [0.614–2.242] [0.453–4.555] [0.182–1.089] [0.035–3.566] [1.184–11.907] [0.268–1.943] - [0.085–11.647] [0.4–3.029] [0.245–3.263] |
0.998 0.747 0.567 0.401 0.108 0.7 0.016 0.656 - 0.642 0.7 0.916 |