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Volcano plots of intracellular in-house matched metabolites that differentiate (A) MDA-MB-231 and DOX-RES-50 and (B) MDA-MB-231 and DOX-RES-100. Metabolites are highlighted that have a p < 0.05 and an absolute fold change ≥1.2. Metabolites in red are increased in doxorubicin-resistant cell line samples and metabolites in blue are decreased in doxorubicin-resistant cell line samples.
