Table 2.
Composition and labeling of blank 2% solid lipid nanoparticles (SLNs) used in pre-formulation studies. Abbreviations: Cp: cholesteryl palmitate; Hh: hexadecyl hexadecanoate (cetylpalmitate); Sp: Span; Tm: Trimyristin; Tw: Tween.
| Lipid (2%) | Sp Grade | Sp and Tw Ratio | ||
|---|---|---|---|---|
| 4% Sp 4, 8% Tw20% | 2% Sp, 5% Tw20 | 4% Sp, 5% Tw20 | ||
| Tp | Sp60 | SLNs 2% Tp 4% Sp60 8% Tw20 | SLNs 2% Tp 2% Sp60 5% Tw20 | - |
| Tm | Sp60 | SLNs 2% Tm 4% Sp60 8% Tw20 | SLNs 2% Tm 2% Sp60 5% Tw20 | - |
| Cp | Sp60 | SLNs 2% Cp 4% Sp60 8% Tw20 | SLNs 2% Cp 2% Sp60 5% Tw20 | - |
| Hh | Sp60 | SLNs 2% Hh 4% Sp60 8% Tw20 | SLNs 2% Hh 2% Sp60 5% Tw20 | - |
| Sp40 | SLNs 2% Hh 4% Sp40 8% Tw20 | - | - | |
| Sp80 | SLNs 2% Hh 4% Sp80 8% Tw20 | SLNs 2% Hh 2% Sp80 5% Tw20 | SLNs 2% Hh 4% Sp80 5% Tw20 | |