Table 5.

Physicochemical characterization of blank (2% hexadecyl hexadecanoate-Hh, 2% Span80-Sp80, 4% Tween20-Tw20), α-tocopherol (TOCO) loaded and 6-coumarin (6-cum) and TOCO co-loaded solid lipid nanoparticles (SLNs) purified by size exclusion. Abbreviations: PDI: polydispersion Index.

	Mean Size (nm)	PDI	Loaded Compound Concentration after Purification (μg/mL)
Blank SLNs	297.2 ± 4.1	0.185	-
TOCO SLNs	108.6 ± 0.8	0.162	2250 ± 250
6-cum TOCO SLNs	97.0 ± 0.1	0.102	TOCO: 2990 ± 304 6-cum: 15.2 ± 2.3