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. 2023 Jun 30;11(7):569. doi: 10.3390/toxics11070569

Table 1.

Weekly body weight gain and relative liver weight of male rats during the CPF or IM treatment experimental period and the ameliorating effect of pomegranate-extract-loaded clove-oil-based nanoemulsion.

Group Initial bw (g) Final bw (g) Weekly
bw Gain (g)
% of Weekly
bw Gain
Liver
Weight
Relative
Liver Weight
I 142.00 ± 2.30 220.80 ± 2.60 ab 19.70 ± 0.80 a 100.00 6.88 ± 0.63 cd 3.11 ± 0.26 cd
II 142.80 ± 1.90 220.40 ± 2.40 abc 19.40 ± 1.04 ab 98.48 6.57 ± 0.24 d 2.98 ± 0.12 d
III 145.20 ± 2.20 218.60 ± 1.90 bc 18.35 ± 0.80 bc 93.15 6.89 ± 0.36 bcd 3.15 ± 1.40 cd
IV 146.60 ± 2.10 218.80 ± 2.60 bc 18.05 ± 0.90 c 91.62 7.06 ± 0.43 bcd 3.23 ± 0.21 bc
V 148.20 ± 1.10 218.40 ± 2.30 bc 17.55 ± 0.70 cd 89.09 7.42 ± 0.29 ab 3.39 ± 0.13 ab
VI 149.00 ± 2.40 219.80 ± 1.50 abc 17.70 ± 0.80 cd 89.85 7.08 ± 0.17 bcd 3.22 ± 0.06 bcd
VII 150.40 ± 0.50 217.60 ± 1.10 cd 16.80 ± 0.20 de 85.28 7.39 ± 0.50 abc 3.40 ± 0.24 ab
VIII 149.60 ± 1.90 215.40 ± 1.80 d 16.45 ± 0.90 e 83.50 7.73 ± 0.26 a 3.59 ± 0.10 a
IX 148.00 ± 1.00 222.00 ± 2.10 a 18.50 ± 0.60 bc 93.91 6.92 ± 0.29 bcd 3.12 ± 0.11 cd
X 150.00 ± 1.60 221.80 ± 1.60 a 17.95 ± 0.80 c 91.12 6.71 ± 0.35 d 3.02 ± 0.17 cd

Values are the mean ± S.D. Values with the same letter have insignificant differences at p ≤ 0.05. Control group (I); Pomegranate–clove-oil-based nanoemulsion group (II); Imidacloprid-treated groups (III, IV, and V) which received IM in drinking water at doses of 14, 28, and 54 mg/kg bw/day, respectively; Chlorpyrifos-treated groups (VI, VII, and VIII) which received CPF in drinking water at doses of 1, 2, and 4 mg/kg bw/day, respectively. IM pomegranate–clove-oil-based nanoemulsion treatment group (IX) received IM at the highest dose (54 mg/kg bw/day) plus nanoemulsion at a dose of 50 mg/kg bw/day. CPF pomegranate–clove-oil-based nanoemulsion treatment group (X) received CPF at the highest dose (4 mg/kg bw/day) plus nanoemulsion at the dose of 50 mg/kg bw/day. Weekly body weight (g) = (final bw − initial bw)/no. of weeks. Relative liver weight (%) = (liver weight (g)/final bw (g) × 100). Percentage of weekly bw gain (%) = (Weekly bw gain of treatment/Weekly bw gain of control) × 100.