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Evaluation of apoptosis in A549 cells by 7-AAD assay after 24 h of treatment with DOX, LAP-mPEG/DOX, and LAP-cPEG/DOX. As shown, there was a significant increase in the number of apoptotic cells treated with the LAP-cPEG/DOX formulation compared to the LAP-mPEG/DOX at a DOX concentration of 1.25 (*** p < 0.001).
