Skip to main content
. 2023 Jul 3;30:208–220. doi: 10.1016/j.omtm.2023.06.012

Table 1.

Engineered viruses

Virus name gDa gH gI gE UL24
KNGF Y38 WT WT WT WT
KNGFΔ38 Δ38 WT WT WT WT
KNGF-Eʹ Y38 WT WT V154M WT
KNGF-Iʹ Y38 WT I286F WT WT
KNGF-EʹIʹ Y38 WT I286F V154M WT
KNGF-Hʹ Y38 A732V WT WT WT
KNGF-HʹEʹ Y38 A732V WT V154M WT
KNGF-HʹIʹ Y38 A732V I286F WT WT
KNGF-HʹIʹEʹ Y38 A732V I286F V154M WT
KNGF-24ʹ Y38 WT WT WT C103Y
KNGF-EʹIʹ24ʹ Y38 WT I286F V154M C103Y
KNGF-Hʹ24ʹ Y38 A732V WT WT C103Y
KNGF-HʹEʹIʹ24ʹ Y38 A732V I286F V154M C103Y
J4HΔ38b Δ38 A732V I286F V154M C103Y

All viruses contain gB:NT (D285N/A549T).

a

Viruses contain either gD:ppNGF(Y38), which is able to enter cells via nectin-1, or gD:ppNGF(Δ38), which does not enter cells via nectin-1.

b

J4HΔ38 is a derivative of J4H.