Table 3.
Recurrent copy number variants identified in WBC gDNA and their frequency in the population of dogs with WBC gDNA-specific CNVs.
Chromosome | Gain/Loss | Number of Dogs with This Finding * | % of Dogs with WBC gDNA-Specific CNVs with This Finding * % [95% CI] |
---|---|---|---|
25 | Loss | 46 | 28.1 [21.7, 35.4] |
25 | Gain | 39 | 23.8 [17.6, 31.2] |
16 | Loss | 22 | 13.4 [8.8, 19.8] |
9 | Gain | 21 | 12.8 [8.3, 19.1] |
14 | Gain | 18 | 11.0 [6.8, 17.0] |
13 | Gain | 14 | 8.5 [4.9, 14.2] |
8 | Loss | 13 | 7.9 [4.5, 13.5] |
36 | Gain | 10 | 6.1 [3.1, 11.2] |
* Of the 164 dogs with WBC gDNA-specific CNV(s); Findings were not mutually exclusive. Some dogs had multiple concurrent WBC gDNA findings, either within a single chromosome (e.g., a partial gain and a partial loss of chromosome 25) or affecting multiple chromosomes (e.g., gains on both chromosomes 14 and 25).