Figure 6.

(a) Chemical structure of the amphiphilic dendrimer AD (right) and (b) the computer-derived molecular model of a nanomicelle formed by AD upon self-assembly. Adapted with permission from [64]. Copyright 2023, Elsevier. (c) Chemical structure of the gemcitabine (Gem) conjugated amphiphilic dendrimer and (d) a zoomed snapshot of a nanomicelle formed upon its self-assembly (GemNM) as extracted from the corresponding equilibrated MD simulation. Adapted with permission from [65]. Copyright 2022, Elsevier. In (b), the charged terminal groups are highlighted in a darker green shade while in (d) the Gem moieties are portrayed in orange (in both panels, hydrogen atoms, water molecules, ions and counterions have been omitted for clarity).