Heterogeneity of allergic rhinitis: Inducible mechanistic traits. Adapted from Gerth van Wijk and Smits, 202118 CD8, cluster of differentiation 8; NK, natural killer; Th2, Type 2 helper. Allergic rhinitis patients exhibit heterogeneous clinical traits, including monosenstization to polysensitization for various allergens combined with mild-to-persistent and/or moderate typical rhinitis complaints, together with comorbidities for asthma, such as airway hyperresponsiveness