Table 2.
Overall and species-wise selection pressure on VP6, VP7, and NSP4 genes from UP-SB19, UP-SB 21, and UP-SB 37, along with other isolates of RVC.
| Genes | Significant Codon Sites (p ≤ 0.01) | Total Substitutions/Sites | dN/dS * | Selection Pressure | dN/dS with Porcine | dN/dS with Human |
|---|---|---|---|---|---|---|
| NSP4 UP-SB37 | 66 | 2.673 | 0.2878 | Purifying selection | 0.2907 | 0.2133 |
| VP6 UP-SB21 | 179 | 3.192 | 3.6590 | Positive selection | 3.7696 | 0.0648 |
| VP6 UP-SB37 | 253 | 2.515 | 0.0393 | Purifying selection | 1.718 | 0.0340 |
| VP7 UP-SB37 & UP-SB19 | 79 | 2.291 | 5.4405 | Positive selection | 5.3210 | 4.7483 |
* dN/dS = non-synonymous/synonymous rate ratio.