Figure 5.

TUNEL assay. MCF-7 breast cancer cells were exposed to compounds 7e and ellipticine (E) at their IC₅₀ values, or to the vehicle (DMSO) for 24 h. Then, they were further processed, as reported in Section 4, and imaged under a fluorescence microscope (20× magnification). Panels (A), DAPI λ_ex,em= 350 nm/460 nm; panels (B), CF^TM488A, λ_ex,em = 490 nm/515 nm; panels (C) show the merge channel.