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. 2023 Jun 23;11(7):1136. doi: 10.3390/vaccines11071136

Table 1.

General characteristics of 538 vaccinated healthcare workers (HCWs) subjects by age, gender, and detection of antibodies against the receptor-binding domain (RBD), antibody detection against the S protein, S1 domain, S2 domain, and the detection of the level of antibodies against the nucleocapsid (N) protein of SARS-CoV-2.

Parameters Mean ± SD Median (IQR) Titers after Dilution
Mean ± SD
Titers after Dilution
Median (IQR)
% (N *)
Healthcare workers 538
Age 43.7 ± 12.3 47 (33–53) - - -
Gender
     Male - - - - 49.4% (266)
     Female - - - - 50.6% (272)
anti-N IgG (U/mL)
     <10 1.7 ± 1.9 0.99 (0.99–0.99) - - 65.5% (352)
     [10, 100] 34.3 ± 22.8 26 (16–45) - - 31.0% (167)
     >100 - - 440.4 ± 338.8 306 (201.75–625) 3.5% (19)
anti-RBD IgG (U/mL)
     <10 5.0 ± 2.8 5 (4, 6) - - 0.4% (2)
     [10, 100] 49.8 ± 34.2 40 (25.75–76) - - 1.1% (6)
     >100 - - 1485.04 ± 311.10 1600 (1600–1600) 98.5% (530)
anti-S1 IgG (U/mL)
     <10 5.0 - - - 0.2% (1)
     [10, 100] - - - - 0.0% (0)
     >100 - - 1357.2 ± 434.8 1600 (1284.75–1600) 99.8% (537)
anti-S2 IgG (U/mL)
     <10 5.2 ± 2.4 5(3–7) - - 13.5% (73)
     [10, 100] 40.0 ± 24.9 33.5(19–54) - - 70.3% (378)
     >100 - - 156.8 ± 148.7 125 (80–189) 16.2% (87)

* N = the number and percentage of subjects in parentheses for every antibody-tested level.