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. 2023 Jul 4;15(7):1885. doi: 10.3390/pharmaceutics15071885

Figure 4.

Figure 4

Anti-androgenic and anti-lipogenic effects of FRO on DHT-treated LNCaP cells (A) LNCaP cells were treated with the indicated concentrations of FRO for 24 h (n = 3). An MTS assay was used to measure cell viability. The results are presented as the mean ± SD of three independent experiments. * p < 0.05 and *** p < 0.001 versus control groups. (B) DHT-treated SEB-1 cells were treated with FRO (100 μg) for 24 h. Cell lysates were subjected to Western blotting to analyze the levels of AR, 5α- reductase, SREBP-1, FAS, and β-actin. The results are presented as the mean ± SD of three independent experiments. ## p < 0.01, ### p < 0.001 (control versus DHT-induced control), ** p < 0.01, and *** p < 0.001 versus the DHT-induced control group.