Table 2.
Biological activities of mono-aromatic steroids (28–52).
| No. | Dominated Biological Activity (Pa) * | Additional Predicted Activities (Pa) * |
|---|---|---|
| 28 | Anti-hypercholesterolemic (0.961) Proliferative diseases treatment (0.711) |
Anti-neoplastic (0.840) Apoptosis agonist (0.787) |
| 29 | Neuroprotector (0.979) Respiratory analeptic (0.970) Anti-neoplastic (0.888) |
Anti-hypercholesterolemic (0.953) Anti-infective (0.933) Anti-protozoal (Leishmania) (0.922) |
| 30 | Anti-hypercholesterolemic (0.860) Anti-inflammatory (0.754) |
Anti-neoplastic (0.805) Chemopreventive (0.721) |
| 31 | Anti-hypercholesterolemic (0.907) Anti-inflammatory (0.765) |
Anti-neoplastic (0.836) Apoptosis agonist (0.788) |
| 32 | Anti-hypercholesterolemic (0.764) | Anti-inflammatory (0.695) |
| 33 | Anti-hypercholesterolemic (0.929) | Respiratory analeptic (0.885) |
| 34 | Anti-hypercholesterolemic (0.935) | Apoptosis agonist (0.850) |
| 35 | Anti-hypercholesterolemic (0.950) Anti-Parkinsonian, rigidity relieving (0.875) |
Apoptosis agonist (0.898) Anti-neoplastic (0.880) |
| 36 | Anti-hypercholesterolemic (0.806) | Anti-neoplastic (0.729) |
| 37 | Anti-hypercholesterolemic (0.914) Hypolipemic (0.858) |
Apoptosis agonist (0.894) Anti-neoplastic (0.879) |
| 38 | Anti-neoplastic (0.922) | Immunosuppressant (0.774) |
| 39 | Anti-neoplastic (0.899) Apoptosis agonist (0.896) |
Anti-inflammatory (0.795) |
| 40 | Neuroprotector (0.829) | Anti-allergic (0.731) |
| 41 | Anti-convulsant (0.877) | |
| 42 | Apoptosis agonist (0.828) Anti-neoplastic (0.798) |
Anti-inflammatory (0.813) |
| 43 | Anti-neoplastic (0.782) | Anti-bacterial (0.736) |
| 44 | Acute neurologic disorders treatment (0.867) | Anti-neoplastic (0.797) |
| 45 | Anti-inflammatory (0.825) | Apoptosis agonist (0.793) |
| 46 | Anti-neoplastic (0.884) | Apoptosis agonist (0.848) |
| 47 | Anti-neoplastic (0.799) | Apoptosis agonist (0.716) |
| 48 | Anti-neoplastic (0.858) | Anti-hypercholesterolemic (0.839) |
| 49 | Anti-neoplastic (0.858) | Cell adhesion molecule inhibitor (0.795) |
| 50 | Anti-neoplastic (0.841) | Immunosuppressant (0.722) |
| 51 | Anti-neoplastic (0.844) | Apoptosis agonist (0.792) |
| 52 | Apoptosis agonist (0.706) | Acute neurologic disorders treatment (0.768) |
* Only activities with Pa > 0.7 are shown.