Skip to main content
. 2023 Jul 10;16(7):985. doi: 10.3390/ph16070985

Table 1.

LogD7.4 and stability in PBS and mouse serum of 203Pb-labeled DOTAM-TATE, eSOMA-01, eSOMA-02, and eSOMA-03.

Compound LogD7.4 b Stability in PBS(%) a Stability in PBS(%) a
1 h 4 h 24 h 1 h 4 h 24 h
[203Pb]Pb-DOTAM-TATE −1.41 ± 0.01 99 99 99 99 99 99
[203Pb]Pb-eSOMA-01 −1.99 ± 0.03 100 100 100 100 100 100
[203Pb]Pb-eSOMA-02 −1.88 ± 0.03 97 97 97 97 97 97
[203Pb]Pb-eSOMA-03 −1.36 ± 0.06 70 40 15 85 70 60

a Results are expressed as a percentage of intact labeled ligand after incubation at 37 °C (n = 1); b n = 3.