Figure 7.

Summary of valence processing in the STN and prefrontal cortex using the MID task. We highlight our main physiological findings using the MID task dissociating reward and loss valence and anticipatory and outcome processes. Delta power is increased in the anticipatory phase across both reward and loss valences and acts as a potential marker of motivation. In contrast, gamma activity shows potential valence-specificity particularly during the anticipation of losses. In the outcome phase, delta power is elevated only during reward outcomes and is observed in both the prefrontal cortex and STN with enhanced coherence. Although loss outcomes do not show a main effect of power differences, lower delta activity to loss outcomes correlates with greater addiction severity.