Photomicrographs showing the patohistological analysis. Liver tissue needle biopsy samples and heterogeneous findings, with blue arrows marking necro-inflammatory activity, and red arrows marking reticulin fibers, (A) showing moderate necro-inflammatory activity—A2, METAVIR score, from HIV/HCV co-infected patient, hematoxylin–eosin stain, magnification 10×; (B) cirrhosis—F4, METAVIR score, from HIV/HCV co-infected patient, reticuline-silver stain, magnification 10×; (C) mild necro-inflammatory activity—A1, METAVIR score, from HCV-infected patient, hematoxylin–eosin stain, magnification 10×; (D) moderate fibrosis, periportal with few septa—F1, METAVIR score, from HCV-infected patient; reticuline-silver stain, magnification 10×; (E) minimal necro-inflammatory activity, hematoxylin–eosin stain—A1, METAVIR score, from HIV-infected patient,, magnification 10×; (F) no fibrosis—F0, METAVIR score, from HIV-infected patient, reticuline-silver stain, magnification 10×.