Table 1.
Total demand and total standardized demand for specific immunoglobulin, expressed in International Units and International Units per capita and per 1000 population, and variations in percentage between 2017 and 2021 (adapted by the Italian National Blood Centre on data from the Traceability information flow, Ministry of Health and the Italian Medicines Agency).
| Total Demand | Total Demand (Per Capita) | Δ% 2021 vs. 2017 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2017 | 2018 | 2019 | 2020 | 2021 | 2017 | 2018 | 2019 | 2020 | 2021 | ||
| CMV IG | 15,781,000 | 14,333,000 | 15,490,000 | 12,690,000 | 14,455,000 | 0.26 | 0.24 | 0.26 | 0.21 | 0.24 | −8.40% |
| Hepatitis B IG (SQ/IM use) | 64,575,800 | 57,886,180 | 75,488,160 | 70,073,140 | 62,879,640 | 1.07 | 0.96 | 1.25 | 1.17 | 1.06 | −2.63% |
|
Hepatitis B IG
(IV use) |
23,047,100 | 17,885,500 | 16,150,000 | 14,655,500 | 14,362,500 | 0.38 | 0.30 | 0.27 | 0.25 | 0.24 | −37.68% |
| Tetanus IG | 141,258,000 | 131,772,250 | 147,042,000 | 124,246,683 | 117,126,250 | 2.33 | 2.18 | 2.44 | 2.08 | 1.98 | −17.08% |
| Total Demand | Total Demand (*1000 population) | ||||||||||
| Rabies IG | 84,000 | 111,150 | 185,550 | 134,850 | 108,150 | 1.39 | 1.84 | 3.07 | 2.26 | 1.83 | 28.75% |
|
Varicella-
zoster IG |
195,750 | 179,625 | 86,625 | 69,500 | 111,000 | 3.23 | 2.97 | 1.44 | 1.17 | 1.87 | −43.30% |
IG—immunoglobulin; SQ—subcutaneous; IM—intramuscular; IV—intravenous; *—per.