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. 2023 Jul 5;13(7):824. doi: 10.3390/metabo13070824

Figure 2.

Figure 2

Bile acid concentrations in the liver of the WT and DKO groups. (A) Concentration of all BA types conjugated with and without taurine. Data are the mean ± SE. The white circle in the column shows the individual value. * p < 0.05, ‡ p < 0.0001 compared to the respective BA in the WT group by two-way ANOVA post hoc Bonferroni’s multiple comparison test. Abbreviations: U, unconjugated form (plane column); T, taurine-conjugated form (striped column). (B) TBA concentration (the sum of all BA types of unconjugated and taurine-conjugated forms). Data are the mean ± SE. ** p < 0.01 according to unpaired Student’s t-test. (C) BA composition (the sum of unconjugated and taurine-conjugated forms). Pie graph was constructed using the mean of each BA. ‡ p < 0.0001 according to chi-square test. (D) The ratio of taurine-conjugated BAs. Data are the mean ± SE. ‡ p < 0.0001 according to unpaired Student’s t-test.