Table 1.
Top Ten Biological Processes in H5N1 Infection. Colour map indicates; Red colour: Low value, Yellow colour: Medium value, Green colour: High value.
| Gene Ontology Terms | Genes | Count | p-Value | Fold Enrichment | FDR |
|---|---|---|---|---|---|
| Cellular response to virus | CXCL10, IL6, CHUK, IRF3, IFNA1, IFNB1, MIR21, MAPK14 | 8 | 3.06 × 10−10 | 46.05366726 | 2.19 × 10−7 |
| Positive regulation of the apoptotic process | PYCARD, IL6, JUN, MAPK8, UBD, TNFSF10, MIR21, SCRIB, SOD1 | 9 | 2.00 × 10−7 | 13.58442777 | 7.15 × 10−5 |
| Defence response to virus | PYCARD, IFITM3, IL6, ITCH, IRF3, IFNA1, IFNB1, RIGI | 8 | 3.13 × 10−7 | 16.99834929 | 7.46 × 10−5 |
| Inflammatory response | PYCARD, CRP, IKBKB, CXCL10, IL6, ITCH, CXCL8, CHUK, NFE2L2 | 9 | 1.12 × 10−6 | 10.81478715 | 1.76 × 10−4 |
| Cellular response to cadmium ion | JUN, MAPK8, CHUK, SUMO1, SOD1 | 5 | 1.23 × 10−6 | 60.37523452 | 1.76 × 10−4 |
| Positive regulation of I-kappaB kinase/NF-kappaB signalling | IKBKB, CHUK, IRF3, CASP10, UBD, TNFSF10, MAP3K7 | 7 | 1.89 × 10−6 | 18.04967949 | 2.00 × 10−4 |
| Cellular response to lipopolysaccharide | PYCARD, CXCL10, IL6, MAPK8, CXCL8, MIR21, MAPK14 | 7 | 1.95 × 10−6 | 17.95615783 | 2.00 × 10−4 |
| Positive regulation of gene expression | CRP, IL6, MAPK8, CXCL8, FN1, MIR21, MAPK14, RIGI, NFE2L2 | 9 | 5.95 × 10−6 | 8.635062612 | 5.32 × 10−4 |
| Cellular response to tumour necrosis factor | PYCARD, IKBKB, CXCL8, CHUK, MAPK14, NFE2L2 | 6 | 9.48 × 10−6 | 20.34562698 | 7.54 × 10−4 |
| Positive regulation of transcription from RNA polymerase II promoter | IKBKB, CXCL10, IL6, JUN, CHUK, IRF3, IFNB1, NCL, MAPK14, RIGI, NFE2L2, RUNX1 | 12 | 1.33 × 10−5 | 4.934321492 | 9.55 × 10−4 |
| Colour map | Low | Medium | High | ||