Table 2.
Top Ten Cellular Components in H5N1 Infection. Colour map indicates; Red colour: Low value, Yellow colour: Medium value, Green colour: High value.
| Gene Ontology Terms | Genes | Count | p-Value | Fold Enrichment | FDR |
|---|---|---|---|---|---|
| Extracellular region | CRP, CXCL8, IFNA1, IFNB1, SFTPD, FN1, MAPK14, SOD1, PYCARD, CXCL10, IL6, CD209, TNFSF10, ST3GAL4 | 14 | 6.79 × 10−5 | 3.466994255 | 0.004652 |
| IkappaB kinase complex | PYCARD, IKBKB, CHUK | 3 | 6.94 × 10−5 | 225.956044 | 0.004652 |
| Extracellular space | CRP, CXCL10, IL6, CXCL8, IFNA1, IFNB1, MIR141, SFTPD, TNFSF10, FN1, MIR21, SOD1 | 12 | 5.53 × 10−4 | 3.264586806 | 0.02468 |
| Nucleoplasm | NDUFA13, JUN, CHUK, SCRIB, MAPK14, SOD1, RUNX1, PYCARD, NXF1, ITCH, MAPK8, IRF3, SUMO1, UBD, NCL, NUP98, NFE2L2 | 17 | 0.001021 | 2.261651041 | 0.034211 |
| Cytosol | JUN, FYB1, CHUK, MAPK14, SOD1, PYCARD, IKBKB, NXF1, ITCH, NRAS, MAPK8, IRF3, SUMO1, CASP10, UBD, NUP98, MAP3K7, RIGI, NFE2L2 | 19 | 0.00521 | 1.818037135 | 0.139638 |
| Nuclear pore | NXF1, SUMO1, NUP98 | 3 | 0.012799 | 17.00744417 | 0.280061 |
| Cytoplasm | NDUFA13, CHUK, MIR21, MAPK14, SOD1, PYCARD, IKBKB, NXF1, ITCH, MAPK8, IRF3, CASP10, CD209, UBD, NCL, MARCHF8, RIGI, NFE2L2 | 18 | 0.01463 | 1.701964463 | 0.280061 |
| CD40 receptor complex | IKBKB, CHUK | 2 | 0.020147 | 95.86013986 | 0.337459 |
| Nuclear inclusion body | NXF1, NUP98 | 2 | 0.023767 | 81.11242604 | 0.353867 |
| Macromolecular complex | PYCARD, IFITM3, ITCH, FYB1, SOD1 | 5 | 0.039911 | 3.749863224 | 0.480924 |
| Colour map | Low | Medium | High | ||