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. 2023 Jul 14;15(14):3138. doi: 10.3390/nu15143138

Table 3.

Changes in endothelial function biomarkers after black garlic consumption (mean and standard deviation).

Biomarker Group Baseline Final Inter-Group
p-Value
Baseline
Intra-Group
p-Value
Time
Inter-Group
p-Value
Final
MCP-1
(pg/mL)
Hypercholesterolemia 875.4 ± 224.5 753.9 ± 240 0.120 0.007 * 0.225
Healthy 779.1 ± 255.1 722.8 ± 242.2 0.015 *
VCAM-1
(ng/mL)
Hypercholesterolemia 1157.3 ± 217 1012.9 ± 202.9 0.655 <0.001 * 0.433
Healthy 1124.4 ± 344.8 1041 ± 301.5 0.061
ICAM-1
(ng/mL)
Hypercholesterolemia 370.2 ± 53.2 330.9 ± 53 0.034 <0.001 * 0.038 #
Healthy 403.7 ± 67.9 340.2 ± 51.3 <0.001 *
P-Selectin
(ng/mL)
Hypercholesterolemia 161.9 ± 29.9 174.8 ± 31.9 0.244 0.002 * 0.345
Healthy 152.6 ± 32.5 179.1 ± 39.2 <0.001 *
E-Selectin
(ng/mL)
Hypercholesterolemia 52.9 ±16.8 57.1± 16.7 0.146 0.012 * 0.014 #
Healthy 59.5 ± 17.5 67.8 ± 18.7 0.002 *
Nitric Oxide
(µmol/L)
Hypercholesterolemia 4.7 ± 3.3 5.8 ± 5.4 0.470 0.297 0.839
Healthy 3.9 ± 3.2 4.7 ± 3.8 0.360

* Significant intra-group differences during the intervention (p < 0.05). # Significant differences between groups at the end of the intervention (p < 0.05).