Table 3.
Changes in endothelial function biomarkers after black garlic consumption (mean and standard deviation).
Biomarker | Group | Baseline | Final | Inter-Group p-Value Baseline |
Intra-Group p-Value Time |
Inter-Group p-Value Final |
---|---|---|---|---|---|---|
MCP-1 (pg/mL) |
Hypercholesterolemia | 875.4 ± 224.5 | 753.9 ± 240 | 0.120 | 0.007 * | 0.225 |
Healthy | 779.1 ± 255.1 | 722.8 ± 242.2 | 0.015 * | |||
VCAM-1 (ng/mL) |
Hypercholesterolemia | 1157.3 ± 217 | 1012.9 ± 202.9 | 0.655 | <0.001 * | 0.433 |
Healthy | 1124.4 ± 344.8 | 1041 ± 301.5 | 0.061 | |||
ICAM-1 (ng/mL) |
Hypercholesterolemia | 370.2 ± 53.2 | 330.9 ± 53 | 0.034 | <0.001 * | 0.038 # |
Healthy | 403.7 ± 67.9 | 340.2 ± 51.3 | <0.001 * | |||
P-Selectin (ng/mL) |
Hypercholesterolemia | 161.9 ± 29.9 | 174.8 ± 31.9 | 0.244 | 0.002 * | 0.345 |
Healthy | 152.6 ± 32.5 | 179.1 ± 39.2 | <0.001 * | |||
E-Selectin (ng/mL) |
Hypercholesterolemia | 52.9 ±16.8 | 57.1± 16.7 | 0.146 | 0.012 * | 0.014 # |
Healthy | 59.5 ± 17.5 | 67.8 ± 18.7 | 0.002 * | |||
Nitric Oxide (µmol/L) |
Hypercholesterolemia | 4.7 ± 3.3 | 5.8 ± 5.4 | 0.470 | 0.297 | 0.839 |
Healthy | 3.9 ± 3.2 | 4.7 ± 3.8 | 0.360 |
* Significant intra-group differences during the intervention (p < 0.05). # Significant differences between groups at the end of the intervention (p < 0.05).