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. 2023 Jul 20;16(7):1030. doi: 10.3390/ph16071030

Table 5.

Influence of sex and type of device on CMA.

CMA ICS LABA LAMA LABA-ICS LABA-LAMA
Sex F M F M F M F M F M
Mean 0.219 * 0.202 * 0.664 * 0.714 * 0.787 * 0.802 * 0.402 * 0.440 * 0.867 0.874
Std. deviation 0.281 0.266 0.326 0.311 0.244 0.232 0.306 0.313 0.197 0.189
Median 0.092 0.085 0.740 0.841 0.887 0.899 0.307 0.363 0.978 0.978
% of adherent patients
(CMA ≥ 0.8)
8.69 7.24 46.15 52.93 61.09 63.82 16.07 19.18 74.71 76.19
Device DPI pMDI DPI pMDI DPI pMDI DPI pMDI DPI pMDI
Number of patients 85,985 200,738 74,468 3451 90,912 19,140 555,151 206,691 23,704 1071
Mean 0.377 * 0.116 * 0.701 * 0.502 * 0.796 * 0.856 * 0.417 * 0.480 * 0.883 * 0.654 *
Std. deviation 0.300 0.170 0.316 0.300 0.236 0.200 0.308 0.323 0.183 0.221
Median 0.282 0.056 0.820 0.441 0.892 0.960 0.334 0.403 0.984 0.612
% of adherent patients
(CMA ≥ 0.8)
14.27 1.93 51.34 21.44 62.69 72.06 17.13 23.21 77.94 27.16

CMA = continuous multiple-interval measures of medication availability; F = female; M = male; DPI = dry powder inhaler; pMDI = pressurized metered dose inhaler; * p < 0.001.