Table 1.

Parameters of network models used in this study.

Model type	Fiber diameter (D, nm)	Porosity $(\mathrm{\varphi })$	Isotropic tensor $(\text{Ω})$
1D Parallel a)	1000	0.978	N/A c)
1D Perpendicular a)	1000	0.978
2D Parallel a)	1000	0.955
2D Perpendicular a)	1000	0.955
3D Cubic a)	500	0.984
	1000	0.936
	2000	0.792
Randomly oriented (F30) b)
Group 1	1000	0.991	${\text{Ω}}_{xx}=0.34$, ${\text{Ω}}_{yy}=0.33$, ${\text{Ω}}_{zz}=0.33$
	2000	0.964
	3000	0.922
Group 2	1000	0.992	${\text{Ω}}_{xx}=0.34$, ${\text{Ω}}_{yy}=0.3$, ${\text{Ω}}_{zz}=0.36$
	2000	0.969
	3000	0.933
Group 3	1000	0.991	${\text{Ω}}_{xx}=0.34$, ${\text{Ω}}_{yy}=0.34$, ${\text{Ω}}_{zz}=0.32$
	2000	0.964
	3000	0.922
Randomly oriented (F50) b)
Group 1	1000	0.986	${\text{Ω}}_{xx}=0.34$, ${\text{Ω}}_{yy}=0.3$, ${\text{Ω}}_{zz}=0.36$
	2000	0.943
	3000	0.878
Group 2	1000	0.987	${\text{Ω}}_{xx}=0.34$, ${\text{Ω}}_{yy}=0.3$, ${\text{Ω}}_{zz}=0.36$
	2000	0.949
	3000	0.892
Group 3	1000	0.986	${\text{Ω}}_{xx}=0.34$, ${\text{Ω}}_{yy}=0.3$, ${\text{Ω}}_{zz}=0.36$
	2000	0.949
	3000	0.893

^a)aging ECM-mimetic fibrous network;

^b)young ECM-mimetic fibrous network;

^c)N/A: not applicable.