Table 1.
Overview of the investigated drug products, administered dose, and formulation type.
| Drug | Trade Name | Dose [mg] | Formulation Type |
|---|---|---|---|
| Aprepitant | Emend ® (MSD, Munich, Germany) | 125 | Nanocrystal |
| Celecoxib | Celebrex ® (Pfizer, Vienna, Austria) | 200 | Microcrystal |
| Fenofibrate | Lipidil ® (Viatris, Bad Homburg, Germany) | 200 | Microcrystal |
| Itraconazole | Sempera 7 ® (JANSSEN-CILAG GmbH, Neuss, Germany) | 100 | Amorphous solid dispersion |
| Nimodipine | Nimotop ® (Bayer AG, Leverkusen, Germany) | 30 | Amorphous solid dispersion |
| Ritonavir | Norvir ® (AbbVie, Wiesbaden, Germany) | 100 | Amorphous solid dispersion |