Figure 5.

Twenty proteins with the highest predicted number of binding epitopes with high affinity for twenty-six HLA I haplotypes with high frequency in the global human population. The black bars represent vaccine protein sequences analyzed as control components. Consensus predictions by both programs are shown by grey bars. The sequence size (a) (amino acid) represented by the light grey line. (A). Prediction by NetCTLpan, based on an artificial neural network algorithm. (B). Prediction by NetMHCpan, which combines high-performance predictor data. Both servers were trained on the epitope database IEDB.