Table 2.
Zeranol metabolite concentrations measured using a validated method on the Thermo Q Exactive HF Hybrid Quadrupole-Orbi MS collected from a cohort of pregnant NJ women. Zeranol concentrations have been corrected for urinary dilution by specific gravity as described by Bandera et al. [9]*. For measurements below the reported LOD, %CV has been recorded as an expression of uncertainty
| Zeranol concentration in urine (ng/mL) | |||||||
|---|---|---|---|---|---|---|---|
| Sample ID | bZal | bZol | Zer | aZol | Zan | Zen | ∑mycoestrogen |
| 1 | nd | 0.0454 | 0.0062 | 0.0968 | nd | 0.156 | 0.304 |
| 2 | nd | 0.0221 | nd | 0.149 | nd | 0.0871 | 0.258 |
| 3 | nd | 0.123 | nd | 0.511 | nd | 0.559 | 1.19 |
| 4 | nd | 0.0268 | nd | 0.0574 | nd | 0.0832 (28%) | 0.167 |
| 5 | nd | 0.0247 | nd | 0.166 | nd | 0.179 | 0.369 |
| 6 | nd | 0.232 | nd | 0.948 | 0.0215 (7.5%) | 2.85 | 4.05 |
| 7 | nd | 0.0136 (48%) | nd | 0.122 | 0.0051 (26%) | 0.185 | 0.326 |
| 8 | nd | 0.0379 | nd | 0.0785 | 0.0020 (9.3%) | 0.139 | 0.258 |
| 9 | nd | 0.0582 | nd | 0.0417 (1.6%) | 0.0038 (6.6%) | 0.0760 (9.9%) | 0.180 |
| 10 | nd | 0.0222 | nd | 0.0588 | 0.0017 (33%) | 0.112 | 0.194 |
Bolded values (%) = values approximated below the reported LOD using integrated peak area (%CV)
nd non-detect; no analyte signal was detected at the retention time
∑mycoestrogen = sum of all zeranol metabolites
*MycoestrogenSG corrected = mycoestrogen value/[(SG − 1) × 100]