Table 5:
Estimated effect of treatment at time of vaccination on mean SARS-CoV-2 spike protein IgG based on a multivariable regression model
| Treatment | Estimated effect on mean IgG (95% confidence interval)1 |
P-value1 |
|---|---|---|
| Prednisone dose <10 mg/day (versus non-use) | −0.46(−1.44, 0.51) | 0.35 |
| Prednisone dose >= 10 mg/day (versus non-use) | −1.25 (−3.52, 1.02) | 0.28 |
| Mycophenolate mofetil dose > 1000 (versus lower dose of MMF, non-use, or use of MMF being held) | −2.38 (−3.57, −1.19) | <0.0001 |
| Tacrolimus use | −1.49 (−2.60, −0.37) | 0.0092 |
| Belimumab use | −2.29 (−4.13, −0.45) | 0.015 |
| Anti-hypertensive medication use | −0.58 (−1.18, 0.020) | 0.058 |
1
Estimated effect and p-value based on a multivariable GEE model, adjusting for sex, time since vaccination, time since vaccination squared, and all other treatments in the table.