. Author manuscript; available in PMC: 2024 Nov 1.

Published in final edited form as: Equine Vet J. 2023 Feb 9;55(6):995–1002. doi: 10.1111/evj.13927

Table 1:

Mean± s.d. values for average cell count of protein biomarker expression per crypt in control tissue and horses with SIS.

Biomarker	Control Tissue (mean cells count ± SD)	Resection margin	Euthanised Intra-operatively (mean cells count ± SD)	Euthanised Post-operatively (mean cells count ± SD)	Survived to discharge (mean cells count ± SD)
Ki67	23.62 ± 5.883	Proximal	21.16 ± 4.108	15.45 ± 4.174^*	20.52 ± 5.024
Ki67	23.62 ± 5.883	Distal	20.41 ± 3.098	15.05 ± 4.141^*	20.52 ± 5.191^†
SOX9	23.97 ± 3.830	Proximal	25.63 ± 12.02^†	19.20 ± 5.411	21.89 ± 5.403
SOX9	23.97 ± 3.830	Distal	25.78 ± 13.34^†	18.45 ± 3.486	20.85 ± 5.648
SOX9 and Ki67 (Co-localised)	6.314 ± 2.590	Proximal	5.209 ± 2.903	3.155 ± 2.401	4.754 ± 2.542
SOX9 and Ki67 (Co-localised)	6.314 ± 2.590	Distal	5.500 ± 3.622	3.347 ± 2.186	4.169 ± 2.557
PHH3	2.085 ± 2.051^†	Proximal	1.268 ± 1.688^†	1.848 ± 1.368^†	1.622 ± 1.098^†
PHH3	2.085 ± 2.051^†	Distal	1.397 ± 2.174^†	1.075 ± 0.6146	1.100 ± 0.7688

^†

Denotes all values that were not normally distributed that KW test has been used instead of ANOVA

Denotes all values that were significantly different from control