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. 2023 Jul 29;22:192. doi: 10.1186/s12933-023-01913-5

Table 1.

Epidemiological studies illustrating the association between obesity and AF

Adjusted risk (obesity vs. normal weight) AF Follow up (years)  Definition of obesity Total Time period Country Design Study References
HR 1.54 (male); HR 1.46 (female)  526 13.7 BMI ≥ 30 kg/m2 5282 1979–1999 USA Observational cohort Wang et al. 2004 [25]
HR 2.35 (male); HR 1.99 (female)  533 5.7 BMI ≥ 30 kg/m2 47,589 1993–2001 Denmark Observational cohort Frost et al. 2005 [14]
HR 1.36  1810 10 BMI > 30 kg/m2 8051 1994–2004 USA Retrospective analysis Zacharias et al.2005 [26]
HR 1.65 834 12.9 BMI ≥ 30 kg/m2 34,309 1993–2008 USA Observational cohort Tedrow et al. 2010 [16]
HR 2.04  110 4.6 BMI ≥ 30 kg/m2 271,203 2004–2009 Denmark Observational cohort Karasoy et al. 2013 [17]
HR 2.9  287 1.5 BMI ≥ 30 kg/m2 7169 1999–2009 Sweden Observational cohort Grundvold et al. 2015 [21]
HR 2.41  288 6 BMI ≥ 30 kg/m2 18,290 2000–2007 USA Observational cohort Berkovitch et al. 2016 [18]
HR 1.2  5106 7.5 BMI ≥ 25 kg/m2 389,321 2004–2006 Korea Retrospective analysis Lee et al. 2017 [20]
OR 1.4  1511 8 BMI > 30 kg/m2 67,278 2006–2013 USA Observational cohort Foy et al. 2018 [27]
HR 1.24 1959 4.95 BMI ≥ 25 kg/m2 17,134 2002–2009 Korea Observational cohort Lim et al. 2019 [28]
HR 1.327 196,136 8.17 BMI ≥ 30 kg/m2 9,797,418 2009–2017 Korea Observational cohort Kim et al. 2019 [22]