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. Author manuscript; available in PMC: 2023 Jul 30.
Published in final edited form as: Nano Lett. 2018 Nov 21;18(12):7784–7793. doi: 10.1021/acs.nanolett.8b03558

Table 1.

Pharmacokinetic parameters of CP, ABDN-CP, ABDH-CP, and MSA.

Pharmacokinetic Parameter ABDN-CP ABDH-CP CP MSA
Elimination half-life [h] 16.8 ± 0.5 16.9 ± 0.3 11.2 ± 0.6 34.6 ± 1.9
Area under curve [μM. h] 80.2 ± 1.9 88.3 ± 1.3 38.8 ± 0.8 157.3 ± 4.3

Values are shown as mean ± SD (n = 5 for ABDN-CP, 6 for CP and MSA, and 7 for ABDH-CP). The elimination half -life and the area under curve for ABDN-CP and ABDH-CP are statistically different from that of the CP (P < 0.01) and MSA (P < 0.001).