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. 2023 Jun 30;15(6):e41189. doi: 10.7759/cureus.41189

Table 2. Age, statin status, and dietary breakdown.

AAD, average American diet; CHO, carbohydrate

Study ID Age (years) Statin use Socioeconomic status Control diet
Pieterse et al. (2005) [24] 21 to 57 Six subjects (four in the experimental group and two in the control group) used hypolipidemic agents (statins). Not reported Mixed dietary fats such as margarine or oil. (Other specifics of the control diet were not given.)
Scott et al. (2017) [25] >=50 individuals taking medications interfering with fat absorption (e.g., bile acid sequestrants, ezetimibe) were excluded. Not reported One medium potato or one cup of chickpeas a day.
Wang et al (2015) [1] 21-70 All participants were not taking lipid‐lowering medications or supplements. Not reported The control diet was described as AAD: 34% fat, 51% CHO, and 16% protein.
Zhang et al. (2022) [26] 25-65 Individuals who used medications that would interfere with the study's outcomes, like lipid-lowering medications, were excluded. Not reported Participants randomly allocated to the control arm were given control foods in different combinations to match the energy level of one avocado per day as closely as possible. Foods such as mini bagels, pierogis, fruit juice, waffle, instant oatmeal, and others were provided.
Colquhoun et al. (1992) [27] 37 and 58 The study was silent on statins or lipid-lowering agents. Not reported High-complex-carbohydrate diet (AHA-III) on blood lipid concentrations. (Specifics of this diet were not reported.)
Lichtenstein et al. (2022) [28] >25 Statin intake was not reported in the inclusion or exclusion criteria. Not reported The control diet was described as a Habitual diet (with no specifics).
Madrigal 2008 [29] Did not report age range Was silent on statin. Not reported The control diets were labeled as Rich monosaturated, free monosaturated, and Low monosaturated fats (Without specific mention of types of traditional food names). The first and third diets were designed to simulate a usual diet, and volunteers carried on their normal activities during the trial.