Table 3.
Combined Effect of AKT1 rs2494732-C and rs2494752-G on NAFLD Risk
| Variables | Controls n (%) | NAFLD Cases n (%) | NAFLD Prevalence (%) | OR (95% CI) | P |
|---|---|---|---|---|---|
| 0 | 569 (30.3) | 280 (34.4) | 33.0 | 1.00 (Ref) | |
| 1–2 | 1122 (59.7) | 471 (57.8) | 29.6 | 0.820 (0.677–0.993) | 0.042a |
| 3–4 | 187 (10.0) | 64 (7.9) | 25.5 | 0.683 (0.488–0.957) | 0.027a |
| Trend | 0.824 (0.711–0.955) | 0.010b |
Notes: aP-value of the logistic regression model, adjusted for sex, age, triglycerides and glucose. bP-value of the Cochran–Armitage trend test. Bold type indicates statistically significant results.
Abbreviations: NAFLD, nonalcoholic fatty liver disease; OR, odds ratio; 95% CI, 95% confidence interval.