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. 2023 Jul 17;17:1195220. doi: 10.3389/fnhum.2023.1195220

TABLE 3.

Multivariate linear regression analyses of confounding factors for MTx testing.

Coef. SE t 95% CI P-value
lower upper
MTx-C%
Age > 60 −1.65 2.11 −0.78 −5.84 2.54 0.436
Sex (female) −1.29 1.99 −0.65 −5.23 2.66 0.519
Education (> 6 year) 2.19 2.47 0.89 −2.71 7.10 0.377
Mental job −2.71 2.04 −1.33 −6.77 1.35 0.188
Live alone −4.62 4.92 −0.94 −14.40 5.15 0.350
Sleep hours (> 9) 1.02 2.56 0.40 −4.08 6.11 0.692
Homocysteinemia −1.90 2.35 −0.81 −6.58 2.78 0.422
Diabetics −2.73 2.31 −1.18 −7.32 1.86 0.240
Hypertension 0.97 2.16 0.45 −3.32 5.27 0.653
Hyperlipemia 1.03 2.05 0.50 −3.04 5.09 0.618
Brain trauma 0.66 5.06 0.13 −9.39 10.71 0.896
Number of cerebral infarctions (> 1) −0.46 2.31 −0.20 −5.05 4.13 0.843
The differently affected regions of the AIS (posterior) 3.09 2.01 1.53 −0.91 7.08 0.129
PSCI −14.18 2.13 −6.66 −18.41 −9.95 < 0.001
MTx-RT
Age > 60 0.12 0.07 1.78 −0.01 0.25 0.078
Sex (female) 0.09 0.06 1.41 −0.04 0.21 0.161
Education (> 6 year) −0.03 0.08 −0.34 −0.18 0.13 0.735
Mental job 0.06 0.06 0.87 −0.07 0.18 0.385
Live alone 0.22 0.15 1.42 −0.09 0.52 0.158
Sleep hours (> 9) 0.01 0.08 0.16 −0.15 0.17 0.873
Homocysteinemia 0.04 0.07 0.48 −0.11 0.18 0.630
Diabetics −0.03 0.07 −0.35 −0.17 0.12 0.728
Hypertension 0.03 0.07 0.45 −0.10 0.16 0.651
Hyperlipemia −0.01 0.06 −0.22 −0.14 0.11 0.824
Brain trauma 0.10 0.16 0.62 −0.22 0.41 0.534
Number of cerebral infarctions (> 1) 0.02 0.07 0.29 −0.12 0.16 0.776
The differently affected regions of the AIS (posterior) 0.04 0.06 0.71 −0.08 0.17 0.481
PSCI 0.29 0.07 4.44 0.16 0.43 < 0.001
MTx-CP
Age > 60 −5.39 2.58 −2.09 −10.52 −0.26 0.040
Sex (female) −5.13 2.43 −2.11 −9.96 −0.30 0.038
Education (> 6 year) 1.68 3.02 0.56 −4.32 7.68 0.578
Mental job −3.18 2.50 −1.27 −8.15 1.79 0.207
Live alone −14.61 6.02 −2.43 −26.57 −2.65 0.017
Sleep hours (> 9) 0.72 3.14 0.23 −5.51 6.95 0.819
Homocysteinemia −3.21 2.88 −1.11 −8.93 2.51 0.268
Diabetics −1.51 2.83 −0.53 −7.12 4.11 0.596
Hypertension −1.24 2.65 −0.47 −6.50 4.02 0.641
Hyperlipemia 1.57 2.51 0.63 −3.41 6.55 0.532
MTx-C%
Brain trauma −4.26 6.19 −0.69 −16.55 8.04 0.493
Number of cerebral infarctions (> 1) −1.84 2.83 −0.65 −7.46 3.78 0.518
The differently affected regions of the AIS (posterior) 0.74 2.46 0.30 −4.15 5.63 0.765
PSCI −19.11 2.61 −7.33 −24.29 −13.93 < 0.001

Coef, co-efficiency; CI, confidential interval; MTx-%C, MemTrax percent correct; MTx-RT, MemTrax response time (seconds); MTx-Cp = MTx-%C/MTx-RT; PSCI, post-stroke cognitive impairment; AIS, acute ischemic stroke.