Table 1.
Genotyping of markers associated with antimalarial resistance for patient Day0 and Day28 samples.
| Molecular markers | Day0 | Day28 |
|---|---|---|
| PfCRT* | ||
| alleles | 76 T | 76 T |
| H97 | H97 | |
| C101 | C101 | |
| M343 | M343 | |
| C350 | C350 | |
| G353 | G353 | |
| I356T | I356T | |
| PfCYTb | ||
| allele | Y89 | Y89 |
| PfK13 | ||
| alleles | P441 | P441 |
| F446 | F446 | |
| G449 | G449 | |
| N458 | N458 | |
| M476 | M476 | |
| Y493 | Y493 | |
| R539 | R539 | |
| I543 | I543 | |
| P553 | P553 | |
| R561 | R561 | |
| V568 | V568 | |
| P574 | P574 | |
| C580 | C580 | |
| A675 | A675 | |
| PfMDR1 | ||
| alleles | N86 | N86 |
| 184 F | 184 F | |
| D1246 | D1246 | |
| Copy number | 1 | 1 |
| Plasmepsin-2 | ||
| Copy number | 1 | 1 |
Day0: Day of the first malaria attack and of the first intake of artesunate
Day28: Twenty-eight day after initiating antimalarial treatment for the first malaria attack and day of relapse
PfCRT: Plasmodium falciparum chloroquine resistance transporter
PfCYTb: Plasmodium falciparum cytochrome b
PfK13: Plasmodium falciparum Kelch13 gene
PfMDR1: Plasmodium falciparum multi-drug resistance 1
*PfCRT F145I: no result