Table 1.

Description of the instruments used for the evaluation of all participants

Instrument	Description	Domains/subscales	Score
MoCA29	Paper and pencil cognitive screening test for evaluating mild cognitive impairment.	Attention and concentration, executive functions, memory, language, visuoconstructional skills, calculations, orientation.	Range: 0–30 Higher scores represent better cognitive performance.
18-point CDT52 53	The CDT is an assessment tool where participants are asked to draw a big circle, place the clock numbers and then indicate the time as ‘10 past 11’. An 18-point system will be used to score the test.	Visuospatial, executive function.	Range: 0–18 Scoring system with three main components: (A) assessment of circle integrity (two points); (B) number placement and sequencing (six points); and (C) placement and size of the hands (six points). Additionally, there are two points for representation of the clock’s centre and two points for general gestalt.
Brain on Track33 34	Computerised and self-administered test that allows longitudinal monitoring of cognitive performance.	Attention, memory, executive functions, language, calculation, constructive ability, visuospatial processing.	Range: virtually unlimited (maximum number of correct answers in a fixed time). Higher scores represent better cognitive performance. Scores falling below an expected performance threshold for each age/education group represent a pattern of decline in individual performance.
HADS45	Scale with 14 questions designed to assess anxiety and depression. Patients should answer considering the previous week.	Depression, anxiety.	Range (for each subscale): 0–21 Scores greater than or equal to 11 represent a case of anxiety or depression, as applicable.
PSQI44	Quality of sleep index with 18 questions about the sleeping habits of the patients during the previous month.	Subjective sleep quality, sleep latency, duration of sleep, habitual sleep efficiency, sleep disorders, use of medications for sleep, daytime dysfunction.	Range: 0–21 Scores greater than 5 indicate poor sleep quality.
REM Sleep Behaviour Disorder Single‐Question Screen35	Single screening yes/no question about the classic dream-enactment behaviour in the REM behaviour disorder.	REM sleep behaviour disorder.	A positive answer suggests a presence of REM behaviour Disorder.
STOP-Bang questionnaire46	Screening tool with eight yes or no questions related to the clinical features of sleep apnoea.	Obstructive sleep apnoea (OSA).	Range: 0–8 Each positive answer sum 1 to the final score, with higher scores representing more risk of OSA. Scores equal or greater than three indicate OSA.
9-item PD screening questionnaire38	Screening tool with nine yes or no questions	PD	Range: 0–9 Higher scores indicate higher likelihood of Parkinson’ Disease: unlikely if scores are 0–1; possible if scores are 2–4; and probable if scores are ≥5.
Timed “Up and Go” test40	Test to evaluate the ability of patients to perform sequential locomotor tasks that incorporate walking and turning.	Mobility, gait and balance (ability to stand up from the chair, walking characteristics, presence of ‘freezing’ walking, posture).	5-point Likert scale (normal, discreet, mild, moderate and severe) and global gait diagnosis: normal or altered, with parkinsonism and/or osteoarticular and/or vascular and/or others features.

CDT, Clock Drawing Test; HADS, Hospital Anxiety and Depression Scale; MoCA, Montreal Cognitive Assessment; PD, Parkinson’s disease; PSQI, Pittsburgh Sleep Quality Index; REM, rapid eye movement.