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. 2023 Jul 24;9(3):20552173231187810. doi: 10.1177/20552173231187810

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© The Author(s), 2023

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Multivariate regression models of the association between EDSS and separately: (A) QoL (n = 9821) and (B) costs (n = 7286). QoL (measured using German value set); multivariate regression model was adjusted for age, living status, sex, time since last relapse, time since MS diagnosis, time since manifestation, time since last DMT change, number of relapses in previous year, time since last confirmed progression event, current DMT use, educational attainment, MS subtype, and included NTD center as a random effect. CI, confidence interval; DMT, disease-modifying therapy; EDSS, Expanded Disability Status Scale; MS, multiple sclerosis; NTD, NeuroTransData; QoL, quality of life.