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Potential impact of male sex on spinal progression. Given the fact that baseline spinal radiographic damage is known to be a major predictor for further radiographic progression, the diagram represents the putative effect of male sex (X) on spinal radiographic progression in the next 2 years (Y), either directly or indirectly via affecting baseline radiographic damage (baseline mSASSS or baseline presence of syndesmophytes). mSASSS, modified Stoke Ankylosing Spondylitis Spinal Score.
