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. 2022 Apr 10;52(4):1223–1234. doi: 10.55730/1300-0144.5427

Table 6.

Venom immunotherapy protocols with omalizumab.

Patient 1 Patient 2
Systemic reaction with 4. vial 0.8 cc dose of immunotherapy Systemic reaction with 4. vial 0.6 cc dose of immunotherapy
week 0: 150 mg omalizumab week 0: 150 mg omalizumab
week 1: 4. vial 0.3 cc week 2: 4. vial 0.4 cc (with 150 mg omalizumab before 4 h), no reaction
week 2: 4. vial 0.4 cc (with 150 mg omalizumab before 4 h), no reaction week 3: 4. vial 0.5 cc, no reaction
week 3: 4. vial 0.5 cc, no reaction week 4: 4. vial 0.6 cc (with 150 mg omalizumab before 4 h), no reaction
week 4: 4. vial 0.6 cc (with 150 mg omalizumab before 4 h), no reaction week 5: 4. vial 0.7 cc, no reaction
week 5: 4. vial 0.7 cc, systemic reaction with chills, hypotension, cough and dyspnea week 6: 4. vial 0.8 cc (with 150 mg omalizumab before 4 hours), no reaction
week 7: 4. vial 0.9 cc, no reaction
week 8: 4. vial 1 cc (with 150 mg omalizumab before 4 hours), no reaction
week 10: 4. vial 1 cc, no reaction
week 13: 4. vial 1 cc, no reaction
week 17: 4. vial 1 cc, systemic reaction with facial erythema and itching, nausea, uvula edema and dyspnea
week 19: 4. vial 0.4 cc (with 150 mg omalizumab before 4 h), systemic reaction with uvula edema, dyspnea, facial erythema and itching