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. 2023 Feb 23;108(8):2044–2058. doi: 10.3324/haematol.2022.281653

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Copyright© 2023 Ferrata Storti Foundation

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Figure 6. — Survival of pediatric acute myeloid leukemia patients with NUP98 translocations. Kaplan Meier estimates of (A) overall survival (OS) and (B) relapse risk (RR) of pediatric NUP98-translocated acute myeloid leukemia (AML) patients with different translocation partners compared to a reference cohort without NUP98 fusions. OS of (C) NUP98-NSD1 and (D) NUP98-X, when divided by NUP98 fusion exon breakpoint. Outcome was also examined for (E) OS and (F) event-free survival (EFS) of NUP98-KDM5A subgroups by chromosome 13 (chr13) status (monosomy 13, del(13q), translocation 13). Abn3: abnormal chr 3.