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. 2023 Feb 16;108(8):2178–2191. doi: 10.3324/haematol.2022.281510

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Figure 5. — The simplified m7-ATLPI has comparable prognostic ability as the original m7-ATLPI. (A) Scoring of the simplified m7-adult T-ceLL leukemia/lymphoma prognostic index (m7-ATLPI). In order to create the simplified m7-ATLPI, the coefficients of the ATL-PI categories and mutation status of the 7 genes were converted to numbers reflecting their original values. After summing these values, scores <-4, -3.5 to 4.5, and >5 points were categorized as low-, intermediate-, and high-risk simplified m7-ATLPI, respectively. (B) Kaplan-Meier overall survival (OS) curves for the training cohort using the ATL-PI and simplified m7-ATLPI. (C) Kaplan-Meier OS curves for the validation cohort using the ATL-PI and simplified m7-ATLPI. Numbers in parentheses show the number of patients with events/number of patients per cohort. ATL-PI low/int/high: low-, intermediate-, or high-risk ATL-PI; Simplified m7-ATLPI low/int/high: low-, intermediate-, or high-risk simplified m7-ATLPI.