Table 4.

Correlation of Mean Weight Gain With Mean Change in Metabolic Parameters

Parameter	All trials				Duration ≤13 wk				Duration >13 wk
	No. of studies	Coefficient	P	R2	No. of studies	Coefficient	P	R2	No. of studies	Coefficient	P	R2
Blood glucose	12	0.27	.39	0.08	7	−1.60	.06	0.54	5	0.73	.43	0.22
Insulin	7	−0.55	.37	0.16	4	−0.60	.87	0.02	3	−0.19	.56	0.41
HOMA-IR	5	−0.03	.80	0.03	4	−0.21	.40	0.36	1	NA	NA	NA
Total cholesterol	10	0.21	.84	0.01	6	−0.9	.64	0.06	4	6.58	.32	0.46
Triglycerides	10	−0.78	.65	0.03	6	−4.51	.39	0.19	4	−4.54	.71	0.08
LDL cholesterol	7	0.98	.16	0.35	4	1.56	.12	0.78	3	5.57	.23	0.88
HDL cholesterol	10	−0.95	.01	0.60	6	−2.03	.11	0.52	4	0.29	.75	0.06

Abbreviations: HDL, high-density lipoprotein; HOMA-IR, Homeostatic Model Assessment for Insulin Resistance; LDL, low-density lipoprotein; NA, not applicable.