Figure 1.

Development, tuning, internal validation, and external validation set generation. Schematic representation of the dataset creation and analysis strategy, which was devised to assure a robust and reliable dataset for training, validating, and testing of the network. Once a patient's data were placed in one of the datasets, that individual's data were used only in that set, avoiding “cross-contamination” among the development, tuning, and validation sets. External validation sets were collected only for patients who visited the Jingjhou branch, while others were not. The details of the flow chart and how each of the datasets was used are described in the Methods section.