Figure 6.

Mass resolution as a function of analyte charge for a 1 s trapping period using the HAR-based method. The experimentally observed resolution for rTMV disk stacks ranging in mass from ~600–2700 kDa (blue points) and observed resolutions for AAV9 formed from three different solutions (black points) show an increasing deviation from the theoretical instrument resolution (red points) with increasing mass and nonvolatile salt concentration, indicating that sample heterogeneity can limit mass resolution for analyte even in the low MDa mass range.