Table 1.
Preoperative symptoms, therapeutic interventions, and clinical outcome of included studies.
| Preoperative symptoms, n (%) | Surgical intervention, n (%) | ||||||
|---|---|---|---|---|---|---|---|
| References | Swelling | Pain | Sensory deficit | Motor weakness | GTR | STR | Adjuvant/neoadjuvant RT |
| Maiuri et al.29 | 4 (100.0) | 2 (50.0) | –– | –– | 4 (100) | –– | No |
| Ganju et al.26 | 55 (514) | 65 (60.7) | 21 (19.6) | 35 (32.7) | 77 (71.9) | 34 (31.7) | No |
| Huang et al.1 | 13 (29.5) | 31 (70.4) | 27 (61.3) | 23 (52.3) | NA | NA | NA |
| Binder et al.23 | 15 (60.0) | 15 (60.0) | 11 (44.0) | 3 (12.0) | 16 (64.0) | 9 (36.0) | No |
| Rawal et al.34 | 3 (100.0) | 2 (66.6) | 1 (33.3) | 1 (33.3) | 3 (100.0) | –– | One patient received adjuvant RT |
| Seinfeld et al.35 | 4 (100.0) | 3 (75.0) | 1 (25.0) | 1 (25.0) | 4 (100.0) | –– | Three patients underwent adjuvant RT (54 Gy in 30 fractions) |
| Ranalli et al. 33 | 3 (60.0) | 5 (100.0) | 4 (80.0) | 1 (20.0) | 4 (80.0) | 1 (20.0) | No |
| Siqueira et al.36 | 15 (83.3) | 12 (66.6) | 5 (27.7) | 6 (33.3) | 14 (77.7) | 4 (22.2) | No |
| Desai et al. 3 | 102 (88.6) | 115 (100.0) | 115 (100.0) | 14 (12.1) | 74 (64.3) | 41 (35.6) | No |
| Tubbs et al.37 | 4 (100.0) | 1 (25.0) | – | 1 (25.0) | 3 (75.0) | 1 (25.0) | No |
| Go et al.2 | 20 (95.2) | 11 (52.4) | 12 (57.1) | 9 (42.8) | 16 (72.7) | 6 (27.3) | No |
| Soltani et al.14 | 10 (76.9) | 10 (76.9) | 7 (53.8) | 3 (23.1) | 10 (76.9) | – | One of the nonoperative patients underwent adjuvant RT |
| Lee et al.28 | 19 (100.0) | 2 (10.6) | 10 (52.6) | 1 (5.3) | 19 (100.0) | – | No |
| Millan et al.30 | 2 (40.0) | 1 (20.0) | 2 (40.0) | 2 (40.0) | 5 (100.0) | – | No |
| Jia et al.13 | 129 (90.1) | – | 68 (47.5) | 12 (8.3) | 128 (89.5) | 10 (6.9) | Seven patients underwent adjuvant RT |
| Graf et al. (2017) | 6 (54.5) | 3 (27.2) | 3 (27.2) | 2 (18.2) | – | – | No |
| Jung et al. 27 | 17 (94.4) | 9 (50.0) | 8 (44.4) | 4 (22.2) | 17 (94.4) | 1 (5.6) | No |
| Bourque et al.24 | – | 1 (33.3) | 1 (33.3) | 1 (33.3) | – | – | Two patients (40 Gy in 15 fractions) |
| Yuce et al.38 | NA | 5 (45.4) | 10 (90.1) | 6 (54.5) | 11 (100.0) | – | No |
| Pressney et al. 32 | NA | NA | NA | NA | NA | NA | NA |
| Dubuisson et al.12 | 12 (70.5) | 15 (88.2) | 10 (58.8) | – | 14 (82.3) | 1 (5.9) | No |
| Gaba et al.25 | 14 (100.0) | 12 (85.7) | 11 (78.5) | 4 (25.6) | 13 (92.8) | 1 (7.2) | No |
| Total (22 articles) | 447 (65.1) | 320 (46.6) | 327 (47.6) | 129 (18.8) | 432 (79.9) | 109 (20.1) | 14 (2.0) |
GTR, gross total resection; NA, not applicable; RT, radiotherapy; STR, subtotal resection.