Table 1.
Baseline variables, intraoperative information, and adjuvant treatment between neoadjuvant therapy followed by surgery and upfront surgery Groups in the whole original cohort
| Neoadjuvant Therapy (N=2959) % | Upfront Surgery (N=10 715) % | P | |
|---|---|---|---|
| Marital status | <0.001 | ||
| Married | 2012 (68.0) | 6641 (62.0) | |
| Unmarried | 947 (32.0) | 4074 (38.0) | |
| Race | 0.021 | ||
| White | 2467 (83.4) | 8749 (81.7) | |
| Black | 262 (8.9) | 958 (8.9) | |
| Other | 230 (7.8) | 1008 (9.4) | |
| Age | <0.001 | ||
| Mean (SD) | 64.4 (9.54) | 67.6 (10.2) | |
| Gender | 0.755 | ||
| Female | 1447 (48.9) | 5275 (49.2) | |
| Male | 1512 (51.1) | 5440 (50.8) | |
| Site | <0.001 | ||
| Head | 2255 (76.2) | 7685 (71.7) | |
| Body/Tail | 429 (14.5) | 2140 (20.0) | |
| Other/Overlapping | 275 (9.3) | 890 (8.3) | |
| Surgery | <0.001 | ||
| Pancreatoduodenectomy | 2312 (78.1) | 7858 (73.3) | |
| Partial pancreatectomy | 315 (10.6) | 1648 (15.4) | |
| Total pancreatectomy | 332 (11.2) | 1209 (11.3) | |
| Examined nodal number | <0.001 | ||
| <10 | 539 (18.2) | 2089 (19.5) | |
| 11–19 | 1133 (38.3) | 4464 (41.7) | |
| 20+ | 1287 (43.5) | 4162 (38.8) | |
| Adjuvant chemotherapy | <0.001 | ||
| No | 1767 (59.7) | 3159 (29.5) | |
| Yes | 1192 (40.3) | 7556 (70.5) | |
| Adjuvant radiotherapy | <0.001 | ||
| No | 2524 (85.3) | 8184 (76.4) | |
| Yes | 435 (14.7) | 2531 (23.6) | |
| T | <0.001 | ||
| T1 | 275 (9.3) | 1733 (16.2) | |
| T2 | 1652 (55.8) | 6218 (58.0) | |
| T3 | 551 (18.6) | 2445 (22.8) | |
| T4 | 481 (16.3) | 319 (3.0) | |
| N | <0.001 | ||
| N0 | 1515 (51.2) | 3548 (33.1) | |
| N1 | 973 (32.9) | 4202 (39.2) | |
| N2 | 471 (15.9) | 2965 (27.7) | |
| Stage | <0.001 | ||
| IA | 148 (5.0) | 962 (9.0) | |
| IB | 826 (27.9) | 1831 (17.1) | |
| IIA | 260 (8.8) | 660 (6.2) | |
| IIB | 825 (27.9) | 4084 (38.1) | |
| III | 900 (30.4) | 3178 (29.7) |