Table 2.

Univariate analyses by anesthetic technique (regional vs. general).

	No./total (%)
Outcome	General (n = 4152)	Regional (n = 4152)	Odds ratio (95% CI)	P	Fragility index
Major morbidity and mortality (composite)	104/4152 (2.5%)	85/4152 (2.0%)	0.81 (0.61–1.09)	0.162	9
Stroke	59/4152 (1.4%)	57/4152 (1.4%)	0.97 (0.67–1.39)	0.852	19
Myocardial infarction	39/4152 (0.9%)	26/4152 (0.6%)	0.66 (0.40–1.09)	0.105	4
Mortality	24/4152 (0.6%)	12/4152 (0.3%)	0.50 (0.25–1.00)	0.045	1
Minor morbidity (composite)	108/4152 (2.6%)	65/4152 (1.6%)	0.60 (0.44–0.81)	< 0.001	16
Unplanned reintubation	44/4152 (1.1%)	20/4152 (0.5%)	0.45 (0.27–0.77)	0.003	7
Ventilator dependence >48h	20/4152 (0.5%)	12/4152 (0.3%)	0.60 (0.29–1.23)	0.156	4
Pneumonia	37/4152 (0.9%)	20/4152 (0.5%)	0.54 (0.31–0.93)	0.024	2
Deep venous thrombosis	1/4152 (0.0%)	2/4152 (0.0%)	2.00 (0.18–22.07)	0.564	5
Pulmonary embolism	3/4152 (0.1%)	3/4152 (0.1%)	1.00 (0.20–4.96)	> 0.999	6
Superficial SSI	12/4152 (0.3%)	15/4152 (0.4%)	1.25 (0.58–2.68)	0.563	7
Deep incisional SSI	6/4152 (0.1%)	4/4152 (0.1%)	0.67 (0.19–2.36)	0.527	4
Organ space SSI	4/4152 (0.1%)	2/4152 (0.0%)	0.50 (0.09–2.73)	0.414	4
Wound dehiscence	3/4152 (0.1%)	1/4152 (0.0%)	0.33 (0.03–3.20)	0.317	4
Sepsis	11/4152 (0.3%)	6/4152 (0.1%)	0.54 (0.20–1.47)	0.225	4
Septic shock	4/4152 (0.1%)	3/4152 (0.1%)	0.75 (0.17–3.35)	0.705	5
Acute kidney injury	3/4152 (0.1%)	3/4152 (0.1%)	1.00 (0.20–4.96)	> 0.999	6
Progressive renal insufficiency	4/4152 (0.1%)	1/4152 (0.0%)	0.25 (0.03–2.24)	0.180	3
Bleeding event	53/4152 (1.3%)	26/4152 (0.6%)	0.49 (0.30–0.78)	0.002	8
Unplanned resource utilization (composite)	271/4152 (6.5%)	254/4152 (6.1%)	0.93 (0.78–1.11)	0.443	27
Unplanned readmission	209/4152 (5.0%)	191/4152 (4.6%)	0.91 (0.74–1.11)	0.356	21
Unplanned reoperation	102/4152 (2.5%)	108/4152 (2.6%)	1.06 (0.81–1.39)	0.675	22
Length of hospital stay, mean (SD), days	1.6 (1.9)	1.4 (2.3)	−0.16 (−0.25 to −0.07)	< 0.001	NA

SSI, surgical site infection.