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Binding of B subunits and T antigens to mutants of the A subunit. Amino acid sequences of repeats 1 to 10 of the A subunit and locations of mutations are shown. Binding of A subunit mutants to Bα, B′, B", and T antigens is expressed as a percentage of wild-type A subunit binding. Values shown are averages from 2 to 4 experiments. Amino acids conserved between repeats are underlined. The locations of α helices and intrarepeat loops are indicated by lines at the top of the figure.
