Table 3.
Unadjusted and adjusted logistic regression analyses for rapid progression in patients with mild to moderate aortic stenosis.
| Univariable | Multivariable | |||
|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | |
| Follow-up durations, year | 0.57 (0.46–0.70) | < 0.001* | 0.59 (0.45–0.76) | < 0.001 |
| Age, year | 1.02 (0.99–1.06) | 0.175* | ||
| Male gender | 2.02 (1.18–3.46) | 0.010* | ||
| Body mass index, kg/m2 | 1.03 (0.96–1.10) | 0.488 | ||
| Smoking ever | 1.02 (0.48–2.17) | 0.967 | ||
| Hypertension | 0.59 (0.31–1.11) | 0.100* | ||
| Diabetes | 1.00 (0.57–1.74) | 0.991 | ||
| Dyslipidemia | 0.98 (0.56–1.72) | 0.951 | ||
| Coronary artery disease | 0.86 (0.43–1.72) | 0.671 | ||
| Creatinine, mg/dl | 0.81 (0.56–1.16) | 0.254 | ||
| CRP, mg/dl | 0.97 (0.90–1.04) | 0.315 | ||
| LDL-C, mg/dl | 1.00 (0.99–1.01) | 0.262 | ||
| LVEDD, mm | 1.03 (0.99–1.08) | 0.141* | ||
| LVESD, mm | 1.07 (1.03–1.11) | 0.002* | ||
| LVEF, % | 0.97 (0.94–0.99) | 0.004* | ||
| A velocity, m/s | 2.78 (0.71–10.8) | 0.144* | ||
| E/e’ ratio | 1.05 (1.01–1.09) | 0.018* | 1.08 (1.01–1.15) | 0.026 |
| Peak aortic jet velocity, per 0.5 m/s increase | 1.57 (1.28–1.93) | < 0.001* | 1.79 (1.18–2.70) | 0.006 |
A, late diastolic mitral inflow velocity; CRP, C-reactive protein; E/e′, Early diastolic velocity of the mitral annulus; LDL-C, low-density lipoprotein cholesterol; LVEDD, left ventricular end-diastolic dimension; LVEF, left ventricular ejection fraction; LVESD, left ventricular end-systolic dimension; RVSP, right ventricular systolic pressure.
*
p value indicates the presence of statistical significance (p < 0.20).